print small

Participating Countries:

Algeria

Argentina

Australia

Austria

Belgium

Bosnia and Herzegovina

Bulgaria

Croatia

Czech Republic

Denmark

Finland

France

FYR of Macedonia

Germany

Greece

Iceland

Ireland

Israel

Italy

Lithuania

Morocco

Netherlands

New Zealand

Poland

Portugal

Romania

Russian Federation

Serbia

Slovenia

Spain

Sweden

Switzerland

Turkey

Ukraine

United Kingdom

United States

Member area provided by LTFE
COST is supported by the EU Framework Programme Horizon 2020
This website is supported by COST

Karlsuhe Institute of Technology

Tell your friend  | 

Hermann-von-Helmholtz-Platz 1
DE76137 Eggenstein-Leopoldshafen
Germany

Contact email:

Visit the website.

Brief presentation of the institution

Karlsruhe Institute of Technology (KIT) is a higher education and research organisation with about 8,900 employees, 21,000 students, and a total annual budget of about 750 million Euros. KIT was established in 2009 as merger of Universität Karlsruhe (founded in 1825) and For­schungszentrum Karlsruhe (founded in 1956), one of the largest research centres in the Helmholtz Association.
KIT’s research profile is characterised by a strong focus on energy technology, nanotechnology and materials research, elementary particle and astroparticle physics as well as climate and environmental research.

Main activities of the Institute for Pulsed Power and Microwave Technology (IHM) are application-oriented research and development aiming to technology transfer to industry and to large-scale research facilities.

The Bioelectrics Group of the Pulsed Power Department contributes to the Helmholtz-Program “Renewable Energies”. The main subject is to advance science and technology for the generation of high-power, repetitive high-voltage-pulses for large mass-flow applications in energy-, environmental-, and bio-technology.

Main Electroporation related topics

 

R&D focusses on:
Energy-efficient processing of microalgae:
PEF treatment of microalgae for energy-saving processing:
- selective cell component extraction, water-soluble components, lipids
- PEF assisted harvesting
- Cell proliferation by nsPEF induced stress reactions
 
PEF treatment of fruit mash for improved cell component release
 
Inactivation of bacteria in wastewater:
- PEF-treatment of highly contaminated wastewater (hospital outlet)
- Combination of conventional processing with PEF treatment
(Identification of synergies)
 
Generator and processing design, development and testing for long component lifetime, ease of operation and public acceptance
- Switching (gas and solid state switching)
- Online process control (impedance measurement)
- HV component design and testing, Electromagnetic compatibility
 
Basic research on
- correlation between temporal and azimuthal membrane voltage dynamics and permeabilization (ns to µs time-scale)
- stress response of plant cells and tissue on nsPEFs.
- properties of voltage sensitive dyes at supra-physiological voltages

 

Main Electroporation related research techniques and equipment

- 2 kJ, 15Hz, 420 kV Marx-Generator
- 1 kJ, 10Hz, 65 kV Pulse forming network generator (2µs)
- 750J, 20Hz, 300 kV mobile pilot facility for fruit mash treatment
- 1kJ, 20Hz, 300 kV mobile pilot facility for dehydration of energy plants
- 1kJ Marx generator for component testing
- High-voltage measurement equipment up to 0,5 MV
- diverse lab-scale pulse generators (10J to several 100J, ns to ms)
- lab- and pilot-scale facilities for microalgae cultivation, harvesting
- fluorescence microscopes (axiovert, axiplan)
- pulsed laser fluorescence microscopy setup: SureliteII NdYAG, 8mJ dye-laser.
- HEKA patch clamp set-up

 

Research topics, techniques and equipment not related to Electroporation

- Pulsed Electron Beam Treatment facilities for surface modification

- High power microwave gyrotrons for fusion plasma heating

- Industrial microwave processing

Brief information on available facilites

- S1-Level Biology Laboratory

- Patch-Clamp Lab

- Laser Lab

Willingness to accept/host visiting researchers

Publications

Projects:

  • Bacterial decontamination
    Project type: National
    Funding: Federal Ministry of Education and Research
  • dehydration of green biomass
    Project type: National
    Funding: Helmholtz Progam Renewable Energy
  • ns-time-resolution membrane voltage measurement
    Project type: National
    Funding: Federal Ministry of Education and Research
  • PEF Conditioning of Microalgae
    Project type: National
    Funding: Helmholtz Progam Renewable Energy
  • Stimulation of microalgae growth and component yield by nsPEF
    Project type: National
    Funding: Baden-Wuerttemberg foundation
  • Sugar beet processing
    Project type: National
    Funding: Industrial

Members:

  • Christian Eing
    Email:

    Position: Researcher
  • Johannes Fleig
    Email:

    Position: Technician
  • Wolfgang Frey
    Email:

    Position: Researcher
  • Martina Goettel
    Email:

    Position: Researcher
  • Christian Gusbeth
    Email:

    Position: Researcher
  • Klaus Leber
    Email:

    Position: Technician
  • Sarah Rocke
    Email:

    Position: Technician
  • Martin Sack
    Email:

    Position: Researcher
  • Aude Silve
    Email:

    Position: Researcher
  • Ralf Straessner
    Email:

    Position: Researcher
  • Lars Wegner
    Email:

    Position: Researcher
  • Ruediger Wuestner
    Email:

    Position: Technician

Project Office

Working groups

Steering Committee

Founding members

DC Rapporteurs

Related sites: