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Participating Countries:

Algeria

Argentina

Australia

Austria

Belgium

Bosnia and Herzegovina

Bulgaria

Croatia

Czech Republic

Denmark

Finland

France

FYR of Macedonia

Germany

Greece

Iceland

Ireland

Israel

Italy

Lithuania

Morocco

Netherlands

New Zealand

Poland

Portugal

Romania

Russian Federation

Serbia

Slovenia

Spain

Sweden

Switzerland

Turkey

Ukraine

United Kingdom

United States

Member area provided by LTFE
COST is supported by the EU Framework Programme Horizon 2020
This website is supported by COST

Universitaet Leipzig / Center for Biotechnology and Biomedicine

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Deutscher Platz 5
04105 Leipzig
Germany

Contact email:

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Brief presentation of the institution

The Center for Biotechnology and Biomedicine, Universität Leipzig has been founded in 2003 and is funded by the European Commission and the Free State of Saxony. The scientifice focus is dedicated to an interdisciplinary topic from proteomics, tissue engineering, mitogenic programming of cells to cell and tissue based microarray technologies for real-time monitoring. Miniaturization, synchronization and nano-structuring promote the sensor technology and microimplant development.

Main Electroporation related topics

Actually, the main topic of biohybrid research are low and high voltage impedanse spectroscopy, voltammetry, microlaser mediated (electro/opto)poration of single cells. Microlaser dissection and optp-injection ( opto-poration of viable cells are combined with real-time monitoring using impedance spectroscopy and time labs microscopy. High resolution microscopy, such as multiphoton laser scanning microscopy and STED mode are established for detectionof sub-cellular alterations in nano-scale. A borad range of microarrays and conductive nanopourous membranes can be fabricated in a cleanroom facility according to photolithography and lift-off technique using polymer, silicon and borosilicate substrates.

Main Electroporation related research techniques and equipment

  • Low and high voltage laboratory (pulsers)
  • Oscilloscopes
  • Multiphoton laser scanning microscope (STED)
  • Microlaser (UV / IR) manipulation and biosensor platform for microdissection and catapultation
  • Impedance analyzers, multiplexer, microcontroller
  • Electronic board for microarrays (microtiterplate arrays, smart chips) for multiparametric bioelectronic monitoring

Research topics, techniques and equipment not related to Electroporation

  • Microarray technology
  • Impedance sensor
  • High dense electrode configurations for field potential recording
  • Semiconductive electrode materials on transparent polymers and borosilicate glasses
  • Biosensing for real-time monitoring
  • optoelectronics / Biophotonics
  • Cell and tissue based microtiterplate-electrode arrays
  • Nanoporous membranes for drug release
  • Microimplants for in vivo recording
  • Cell and tussie Engineering
  • Atomic force microscopy for detection of biomechanical forces and viscoelastic properties

Brief information on available facilites

  • Bioelectronics laboratories
  • Microlaser laboratory with opticel tweezer, UV/IR laser for microdissection/optoinjection, laser stretcher
  • Impedance analyzers, spectrometers
  • Nanospotter
  • AFM, UV/VIS fluorescence spectrometer, ELISA fluorescence reader
  • S1 / S" level laboratories
  • Cell and tissue culture laboratories; gyratory shaker for cluster / sphere cultures
  • Molecular and biochemical analytic laboratories; FACS, QT-PCR, RT-PCR
  • 200-seat auditorium and 50-seat classroom with beamer and conference infrastructure

Willingness to accept/host visiting researchers

Projects:

  • Diagnostische Implantate - Membrantechnologie zum induzierten Öffen und Schließen spannungsgesteuerter Polymere für Cystatin-C Sensor
    Project type: National
    Funding: Federal Ministry of Education and Research
  • SiRe - Stromgetriebene Redoxenzyme für Hydroxylierungsreaktionen
    Project type: National
    Funding: Federal Ministry of Education and Research
  • Stem Cells for relevant efficient extended and normalized toxicology
    Project type: International
    Funding: EU 7th FP

Members:

Project Office

Working groups

Steering Committee

Founding members

DC Rapporteurs

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